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Li-Hong Hu Selected Research

LX2343

8/2017LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy.
9/2016Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance.

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Li-Hong Hu Research Topics

Disease

9Neoplasms (Cancer)
01/2019 - 10/2009
5Type 2 Diabetes Mellitus (MODY)
09/2019 - 05/2008
4Inflammation (Inflammations)
09/2021 - 07/2016
3Lung Neoplasms (Lung Cancer)
07/2016 - 01/2016
3Obesity
06/2010 - 10/2006
2Ulcerative Colitis
09/2021 - 06/2017
2Multiple Myeloma
11/2018 - 06/2017
2Cognitive Dysfunction
08/2017 - 09/2016
2Necrosis
06/2017 - 12/2008
2Amyloid Plaque
01/2017 - 09/2016
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
05/2013 - 03/2007
2Insulin Resistance
08/2010 - 05/2008
1Enteritis
09/2021
1Hyperglycemia
09/2019
1Cardiotoxicity
03/2018
1Carcinoma (Carcinomatosis)
03/2018
1Tauopathies
08/2017
1Colitis
06/2017
1Metabolic Diseases (Metabolic Disease)
01/2017
1Alzheimer Disease (Alzheimer's Disease)
09/2016
1Cardiac Arrhythmias (Arrythmia)
07/2016
1Glucose Intolerance
09/2015
1Virus Diseases (Viral Diseases)
09/2015
1Prostatic Neoplasms (Prostate Cancer)
01/2015
1Adenocarcinoma
05/2013
1Colonic Neoplasms (Colon Cancer)
10/2012
1Sarcoma 180
06/2009
1Arthritis (Polyarthritis)
12/2007
1Hypersensitivity (Allergy)
12/2007
1Colorectal Neoplasms (Colorectal Cancer)
03/2007
1Rheumatoid Arthritis
01/2007
1Syphilis
05/2006

Drug/Important Bio-Agent (IBA)

6bufalinIBA
11/2018 - 05/2013
5Pharmaceutical PreparationsIBA
09/2019 - 10/2009
4Proteins (Proteins, Gene)FDA Link
03/2018 - 09/2015
4Insulin (Novolin)FDA Link
09/2015 - 10/2006
3Glucose (Dextrose)FDA LinkGeneric
09/2019 - 08/2010
3Triglycerides (Triacylglycerol)IBA
09/2015 - 05/2008
3Non-Receptor Type 1 Protein Tyrosine PhosphataseIBA
06/2010 - 10/2006
2LX2343IBA
08/2017 - 09/2016
2Streptozocin (Streptozotocin)FDA Link
08/2017 - 09/2016
2thioflavin TIBA
01/2017 - 09/2016
2chan su (ChanSu)IBA
07/2016 - 07/2015
2Proteasome Endopeptidase Complex (Proteasome)IBA
07/2016 - 01/2015
2Metformin (Glucophage)FDA LinkGeneric
09/2015 - 05/2008
1Toll-Like Receptor 4IBA
09/2021
1NF-kappa B (NF-kB)IBA
09/2021
1eriodictyolIBA
09/2021
1xanthatinIBA
01/2019
1STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
01/2019
1Antineoplastic Agents (Antineoplastics)IBA
03/2018
1Peptide Hydrolases (Proteases)FDA Link
03/2018
1ProdrugsIBA
03/2018
1acetamideIBA
08/2017
1AlbuminsIBA
06/2017
1Therapeutic UsesIBA
06/2017
1Bortezomib (Velcade)FDA Link
06/2017
1Dextran SulfateIBA
06/2017
1Proteasome InhibitorsIBA
06/2017
1Superoxide DismutaseIBA
06/2017
1Congo RedIBA
01/2017
1Recombinant ProteinsIBA
01/2016
1SteroidsIBA
01/2016
1Adenosine Triphosphatases (ATPase)IBA
01/2016
1MatrinesIBA
09/2015
119-norbufadienolideIBA
07/2015
1BufanolidesIBA
07/2015
1fangchinoline (limacine)IBA
01/2015
1TriterpenesIBA
04/2014
1cucurbitaneIBA
04/2014
1Blood Glucose (Blood Sugar)IBA
08/2010
1dihydroberberineIBA
08/2010
1Indicators and Reagents (Reagents)IBA
08/2010
1Aristolactam AIIIaIBA
10/2009
1LigandsIBA
10/2009
1Biological ProductsIBA
10/2009
1Vinorelbine (Navelbine)FDA LinkGeneric
10/2009
1Polo-Like Kinase 1IBA
10/2009
1AmidesIBA
06/2009
1Dinoprostone (PGE2)FDA Link
12/2008
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
12/2008
1Interleukin-6 (Interleukin 6)IBA
12/2008
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
05/2008
1Rosiglitazone (Avandia)FDA Link
05/2008
1BerberineIBA
05/2008
1Electron Transport Complex I (NADH-CoQ Reductase)IBA
05/2008
1Calcium-Calmodulin-Dependent Protein Kinase KinaseIBA
05/2008
1AMP-Activated Protein KinasesIBA
05/2008
1DinitrofluorobenzeneIBA
12/2007
1CollagenIBA
12/2007
1CytokinesIBA
12/2007
1vitamin B 12 factor III (HMQC)IBA
03/2007
1AlkaloidsIBA
01/2007
1ElementsIBA
10/2006
1AntibodiesIBA
05/2006

Therapy/Procedure

3Therapeutics
11/2018 - 05/2008
2Chinese Traditional Medicine (Traditional Chinese Medicine)
07/2016 - 07/2015
1Oral Administration
09/2019
1Drug Therapy (Chemotherapy)
10/2012